Software

Released tools from my research. Each is open source and accompanies a paper.

scEEMS

Single-cell Enhanced Expression Modifier Scores — a machine learning framework for predicting cell-type-resolved brain eQTLs, used to identify variants explaining Alzheimer’s disease heritability.

Code Paper

gruyere

Genome-wide Rare Variant EnRichment Evaluation — a rare-variant association test that leverages functional annotations, applied to Alzheimer disease (published in AJHG, 2025).

Code Paper

parmigiano

An empirical Bayes framework for burden and dispersion rare-variant association tests, used to prioritize rare variants associated with Alzheimer’s disease.

Code Paper

LDmat

Efficiently queryable compression of linkage disequilibrium matrices, released as a Python package on PyPI.

Code PyPI Paper